Any-maze latency to esacpe3/31/2024 ![]() Most of the learning and memory models have been applied to study neurobiology, physiology, pharmacology, and gene engineering. Learning and memory behavior can be displayed through several experimental models. In humans, learning and memory are usually expressed through spoken or written language, whereas the cognitive function of animals can only be expressed through behavior. Learning and memory processes are crucial for an organism’s capability to adapt to environmental changes. IntroductionĪnimal learning and memory have been studied since the beginning of the 20th century. There may be a biological basis for learning in mice. The major histocompatibility complex (MHC) and other alleles may be involved in the acquisition process. The percentage of mice that had learned with MudoEb7 (26.1%) was significantly lower than that of mice without MudoEb7 (51.9% P < 0.05). The percentage of mice that had learned with MudoEb5 (37.9%) was significantly lower than that of mice without MudoEb5 (61.1% P < 0.05). The overall percentage of mice that learned was 46.1%. The H-2 polymorphism was determined with PCR amplification, and the correlation between the alleles and the acquisition process was analyzed. The value of the slope of the latent period was considered an indication for the acquisition process. Mice were trained for 5 consecutive days in the Y-maze. To explore the association between the acquisition process in the Y-maze and H-2 class II polymorphisms in mice. ![]()
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